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COLON-CHIP

Turbo Grant for Joost Hoenderop

Joost Hoenderop.jpg 5 Jul 2017

Joost Hoenderop has been awardered a TURBO grant to develop a novel colon-on-a-chip device that allows co-culturing of anaerobic gut bacteria with intestinal 3D villi-like structures. 

The aim of this new TURBO pre-seed grant is to facilitate research between the University of Twente and the Radboudumc that will increase the possibility of collectively obtaining external funding in the fields of 'health and technology'. Additionally, this program will stimulate the exchange of knowledge and expertise between researchers and students. In the first TURBO-grant call 27 proposals for joint research projects were filed. Four proposals were granted based on scientific quality, feasibility of project and likelihood of obtaining additional funding, innovativeness and (societal) impact.

Colon-on-a-chip

Hypomagnesemia is a common side effect of stomach-acid reducing medicines (PPIs). Recently, PPIs were shown to cause disturbances in the composition of the gut microbiome resulting in low serum magnesium levels. In the project 'COLON-CHIP (Co-culture Of microfLora on eNterocytes in the Complex Host Instestine Physiology), Dimitrios Stamatialis (Twente University) and Joost  Hoenderop, theme Renal disorders will develop a novel colon-on-a-chip device that allows co-culturing of anaerobic gut bacteria with intestinal 3D villi-like structures. This device can be used for large-scale compound testing.

See for more details: http://www.rimls.nl/news/twente-university-radboudumc-collaboration-strengthened/


 


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