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Associate Professor

Dick Thijssen Ph.D.

Associate Professor
Dick Thijssen.jpg

The research from Dick Thijssen is focused on exploring the relationship between physical (in)activity and the development of cardiovascular diseases, specifically examining cardiovascular function and structure. He aims to understand and optimise the effects of exercise training to prevent morbidity and mortality in various (pathology) groups. He is also involved in teaching and supervision of practical traineeships at the Radboud University ((bio)medical students). Also, collaborates with the Liverpool John Moores University (www.ljmu.ac.uk), where his rearch is focused on physiological adaptations to physical (in)activity in humans. 

Related publications

  • Repeated increases in blood flow, independent of exercise, enhance conduit artery vasodilator function in humans.
    Naylor LH, Carter H, FitzSimons MG, Cable NT, Thijssen DHJ, Green DJ.
    documentAm J Physiol Heart Circ Physiol 300: H664-H669, 2011
  • Leg vasoconstriction during head-up tilt in patients with autonomic failure is not abolished.
    Groothuis JT, Thijssen DHJ, Lenders JWM, Deinum J, Hopman MTE.
    documentJ Appl Physiol 110: 416-422, 2011
  • Deep Brain Stimulation of the Periaqueductal Grey Induces Vasodilation in Humans.
    Carter HH, Dawson EA, Cable NT, Basnayake S, Aziz TZ, Green AL, Paterson DJ, Lind CRP, Thijssen DHJ, Green DJ.
    documentInt J Hypertens 57: e24-e25, 2011
  • Exercise and arterial adaptation in humans: uncoupling localized and systemic effects.
    Rowley NJ, Dawson EA, Birk GK, Cable NT, George K, Whyte G, Thijssen DHJ, Green DJ.
    documentJ Appl Physiol 110: 1190-1195, 2011
  • Exercise training improves physical fitness and vascular function in children with type 1 diabetes.
    Seeger JPH, Thijssen DHJ, Noordam K, Cranen MEC, Hopman MTE, Nijhuis-van der Sanden MWG.
    documentDiabetes Obes Metab 13: 382-384, 2011
  • Flow-Mediated Dilation and Cardiovascular Event Prediction: Does Nitric Oxide Matter?
    Green DJ, Jones H, Thijssen D, Cable NT, Atkinson G.
    documentInt J Hypertens 57: 363-369, 2011
  • The impact of exercise training on the diameter dilator response to forearm ischaemia in healthy men.
    Thijssen DHJ, Tinken TM, Hopkins N, Dawson EA, Cable NT, Green DJ.
    documentActa Physiol 201: 427–434, 2011
  • The impact of obesity on physiological responses during prolonged exercise.
    Eijsvogels TMH, Veltmeijer MTW, Schreuder THA, Poelkens F, Thijssen DHJ, Hopman MTE.
    documentInt J Obes 35: 1-9, 2011
  • The Effects of Thoracic and Cervical Spinal Cord Lesions on the Circadian Rhythm of Core Body Temperature.
    Thijssen DHJ, Eijsvogels TMH, Hesse M, Ballak DB, Atkinson G, Hopman MTE.
    documentChronobiol Int 28: 146-154, 2011
  • Exercise and vascular adaptation in asymptomatic humans.
    Green DJ, Spence A, Halliwill JR, Cable NT, Thijssen DHJ.
    documentExp Physiol 96: 57-70, 2010
  • Assessment of flow-mediated dilation in humans: a methodological and physiological guideline.
    Thijssen DHJ, Black MA, Pyke KE, Padilla J, Atkinson G, Harris RA, Parker B, Widlansky ME, Tschakovsky ME, Green DJ.
    documentAm J Physiol Heart Circ Physiol 300: H2–H12, 2011
  • The Impact of Exercise Training on Conduit Artery Wall Thickness and Remodeling in Chronic Heart Failure Patients.
    Maiorana AJ, Naylor LH, Exterkate A, Swart A, Thijssen DHJ, Lam K, O'Driscoll G, Green DJ.
    documentInt J Hypertens 57: 56-62, 2011
  • Vascular Function in Children With Repaired Tetralogy of Fallot.
    de Groot PCE, Thijssen D, Binkhorst M.
    documentAm J Cardiol 106: 851–855, 2010
  • Effect of prolonged walking on cardiac troponin levels.
    Eijsvogels T, George K, Shave R, Gaze D, Levine BD, Hopman MT, Thijssen DH.
    documentAm J Cardiol. 105: 267-272, 2010
  • Impact of age, sex and exercise on brachial and popliteal artery remodelling in humans.
    Green DJ, Swart A, Exterkate A, Naylor LH, Black MA, Cable NT, Thijssen DH.
    documentAtherosclerosis 210: 525-530, 2010
  • Ischemic preconditioning improves maximal performance in humans.
    de Groot PC, Thijssen DH, Sanchez M, Ellenkamp R, Hopman MT.
    documentEur J Appl Physiol 108: 141-146, 2010
  • Impact of inactivity and exercise on the vasculature in humans.
    Thijssen DH, Maiorana AJ, O'Driscoll G, Cable NT, Hopman MT, Green DJ.
    documentEur J Appl Physiol 108: 845-875, 2010
  • Cardiovascular function and the veteran athlete
    Wilson M, O'Hanlon R, Basavarajaiah S, George K, Green D, Ainslie P, Sharma S, Prasad S, Murrell C, Thijssen D, Nevill A, Whyte G.
    documentEur J Appl Physiol 110: 459-478, 2010
  • Waist circumference: a waste of time?
    de Groot PC, Thijssen DH, Hopman MT.
    documentHeart 96: 309-310, 2010
  • Noninvasive Assessment of Subclinical Atherosclerosis in Children and Adolescents.
    Thijssen DHJ.
    documentHypertension 55: 14, 2010
  • Shear Stress Mediates Endothelial Adaptations to Exercise Training in Humans.
    Tinken TM, Thijssen DH, Hopkins N, Dawson EA, Cable NT, Green DJ.
    documentHypertension 55: 312-318, 2010
  • Impact of bed rest on conduit artery remodeling: effect of exercise countermeasures.
    van Duijnhoven NT, Green DJ, Felsenberg D, Belavy DL, Hopman MT, Thijssen DH.
    documentHypertension 56: 240-246, 2010
  • Resistive exercise versus resistive vibration exercise to counteract vascular adaptations to bed rest.
    van Duijnhoven NT, Thijssen DH, Green DJ, Felsenberg D, Belavy DL, Hopman MT.
    documentJ Appl Physiol 108: 28-33, 2010
  • Angiotensin II contributes to the increased baseline leg vascular resistance in spinal cord-injured individuals.
    Groothuis JT, Thijssen DH, Rongen GA, Deinum J, Danser AJ, Geurts AC, Smits P, Hopman MT.
    documentJ Hypertens 28: 2094-2101, 2010
  • Obligatory role of hyperaemia and shear stress in microvascular adaptation to repeated heating in humans.
    Green DJ, Carter HH, Fitzsimons MG, Cable NT, Thijssen DH, Naylor LH.
    documentJ Physiol 588: 1571-1577, 2010
  • Arterial prehabilitation: can exercise induce changes in artery size and function that decrease complications of catheterization?
    Alkarmi A, Thijssen DH, Albouaini K, Cable NT, Wright DJ, Green DJ, Dawson EA.
    documentSports Med 40: 481-492, 2010
  • Impact of Shear Rate Modulation on Vascular Function in Humans.
    Tinken TM, Thijssen DHJ, Hopkins N, Black MA, Dawson EA, Minson CT, Newcomer SC, Laughlin MH, Cable NT, Green DJ.
    documentInt J Hypertens 54: 278-285, 2009
  • Sympathetic vasomotor control does not explain the change in femoral artery shear rate pattern during arm-crank exercise.
    Thijssen DH, Green DJ, Steendijk S, Hopman MT.
    documentAm J Physiol Heart Circ Physiol 296: H180-H185, 2009
  • Does arterial shear explain the magnitude of flow-mediated dilation?: a comparison between young and older humans.
    Thijssen DH, Bullens LM, van Bemmel MM, Dawson EA, Hopkins N, Tinken TM, Black MA, Hopman MT, Cable NT, Green DJ.
    documentAm J Physiol Heart Circ Physiol 296: H57-H64, 2009
  • Does conduit artery diameter vary according to the anthropometric characteristics of children or men?
    Hopkins ND, Green DJ, Tinken TM, Sutton L, McWhannell N, Thijssen DH, Cable NT, Stratton G, George K.
    documentAm J Physiol Heart Circ Physiol 297: 2182-2187, 2009
  • Impact of age, sex, and exercise on brachial artery flow-mediated dilatation.
    Black MA, Cable T, Thijssen DH, Green DJ.
    documentAm J Physiol Heart Circ Physiol 297: H1109-H1116, 2009
  • Retrograde flow and shear rate acutely impair endothelial function in humans.
    Thijssen DH, Dawson EA, Tinken TM, Cable NT, Green DJ.
    documentHypertension 53: 986-992, 2009
  • Impact of Shear Rate Modulation on Vascular Function in Humans.
    Tinken TM, Thijssen DH, Hopkins N, Black MA, Dawson EA, Minson CT, Newcomer SC, Laughin MH, Cable NT, Green DJ.
    documentHypertension 54: 278-285, 2009
  • Effect of functional electrostimulation on impaired skin vasodilator responses to local heating in spinal cord injury.
    van Duijnhoven NT, Janssen TW, Green DJ, Minson CT, Hopman MT, Thijssen DH.
    documentJ Appl Physiol 106: 1065-1071, 2009
  • Is the ratio of flow-mediated dilation and shear rate a statistically sound approach to normalization in cross-sectional studies on endothelial function?
    Atkinson G, Batterham AM, Black MA, Cable NT, Hopkins ND, Dawson EA, Thijssen DH, Jones H, Tinken TM, Green DJ.
    documentJ Appl Physiol 107: 1893-1899, 2009
  • Does physical exercise improve arterial structure nd function in spinal cord-injured individuals?
    Groothuis JT, Hopman MT, Thijssen DH.
    documentJ Rehabil Med 41: 397-398, 2009
  • Brachial Artery blood flow responses to different modalities of lower limb exercise.
    Thijssen DH, Dawson EA, Black MA, Hopman MT, Cable NT, Green DJ.
    documentMed Sci Sports Exerc 41: 1072-1079, 2009
  • Blood redistribution during exercise in subjects with spinal cord injury and controls.
    Thijssen DH, Steendijk S, Hopman MT.
    documentMed Sci Sports Exerc 41: 1249-1254, 2009.
  • Exercise-induced changes in venous vascular function in nonpregnant formerly preeclamptic women.
    Krabbendam I, Maas ML, Thijssen DH, Oyen WJ, Lotgering FK, Hopman MT, Spaanderman ME.
    documentReproductive Sci 16: 414-420, 2009
  • Attenuated peripheral vasoconstriction during an orthostatic challenge in older men.
    Groothuis JT, Thijssen DHJ, Kooijman M, Paulus R, Hopman MT.
    documentAge Ageing 37: 680-684, 2008
  • The impact of baseline diameter on flow-mediated dilation differs in young and older humans.
    Thijssen DH, van Bemmel MH, Bullens LM, Dawson EA, Hopkins ND, Tinken TM, Black MAcHopman MT, Cable NT, Green DJ.
    documentAm J Physiol Heart Circ Physiol 295: H1594–H1598, 2008
  • Heterogeneity in conduit artery function in humans: impact of arterial size.
    Thijssen DH, Dawson EA, Black MA, Hopman MT, Cable NT, Green DJ.
    documentAm J Physiol Heart Circ Physiol 295: H1927–H1934, 2008
  • The effect of bed rest and an exercise countermeasure on leg venous function.
    van Duijnhoven NT, Bleeker MW, de Groot PC, Thijssen DH, Felsenberg D, Rittweger J, Hopman MT.
    documentEur J Appl Physiol 104: 991-998, 2008
  • Endothelium-dependent and -independent vasodilation of the superficial femoral artery in spinal cord-injured subjects.
    Thijssen DH, Kooijman M, de Groot PC, Bleeker MW, Smits P, Green DJ, Hopman MT.
    documentJ Appl Physiol 104: 1387–1393, 2008
  • Point Counterpoint: Exercise training does/does not induce vascular adaptations beyond the active muscle beds.
    Green DJ, Maiorana AJ, Cable NT, Thijssen DH, Hopman MT.
    documentJ Appl Physiol 105: 1002-1007, 2008
  • Flow-mediated dilatation in the superficial femoral artery is nitric oxide mediated in humans.
    Kooijman M, Thijssen DH, de Groot PC, Bleeker MW, van Kuppevelt HJ, Green DJ, Rongen RA, Smits P, Hopman MT.
    documentJ Physiol 586: 1137-1145, 2008
  • Physical (in)activity and endothelium-derived constricting factors: overlooked adaptations.
    Thijssen DH, Rongen GA, Smits P, Hopman MT.
    documentJ Physiol 586: 319-324, 2008
  • Time course of change in vasodilator function and capacity in response to exercise training in humans.
    Tinken TM, Thijssen DH, Black MA, Cable NT, Green DJ.
    documentJ Physiol 586: 5003-5012, 2008
  • Physical risks whilst walking the Nijmegen Four Days Marches in 2007: electrolyte imbalance in 1 in 5 walkers
    Eijsvogels TM, Thijssen DH, Poelkens F, Binkhorst M, Wouters CW, Schouwenberg BJ, Hopman MT.
    documentNed Tijdschr Geneeskd 152: 1571-1578, 2008
  • Vascular adaptations to 8-week cycling training in older men.
    Thijssen DH, de Groot PC, Smits P, Hopman MT.
    documentActa Physiol 190: 221-228, 2007
  • Decreased energy cost and improved gait pattern using a new orthosis in persons with long-term stroke.
    Thijssen DH, Paulus R, van Uden CJ, Kooloos JG, Hopman MT.
    documentArch Phys Med Rehabil 88: 181-186, 2007
  • A causal role for endothelin-1 in the vascular adaptation to skeletal muscle deconditioning in spinal cord injury.
    Thijssen DH, Ellenkamp R, Kooijman M, Pickkers P, Rongen GA, Hopman MT, Smits P.
    documentArterioscler Thromb Vasc Biol 27: 325-331, 2007
  • Endothelin and aged blood vessels: one more reason to get off the couch?
    Thijssen DH, Hopman MT, Levine BD.
    documentHypertension 50: 292-293, 2007
  • Enhanced endothelin-1-mediated leg vascular tone in healthy older subjects.
    Thijssen DH, Rongen GA, van Dijk A, Smits P, Hopman MT.
    documentJ Appl Physiol 103: 852-857, 2007
  • Sympathetic nervous system contributes to the age-related impairment of flow-mediated dilation of the superficial femoral artery.
    Thijssen DH, de Groot P, Kooijman M, Smits P, Hopman MT.
    documentAm J Physiol Heart Circ Physiol 291: H3122-3129, 2006
  • Rapid vascular adaptations to training and detraining in persons with spinal cord injury.
    Thijssen D, Ellenkamp R, Smits P, Hopman M.
    documentArch Phys Med Rehabil 87: 474-481, 2006
  • Local vascular adaptations after hybrid traning in spinal cord-injured subjects.
    Thijssen D, Heesterbeek P, van Kuppevelt D, Duysens, Hopman M.
    documentMed Sci Sports & Exerc 37: 1112-1118, 2005
 

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